Gene DeSanctis began the journey of exploring and producing artwork during the mid-1970s.  After graduating from a school specializing in art and design (Hamilton Technical Institute, formally the Hamilton Art School - once attended by J. E. H. MacDonald and A. J. Casson, both members of the Canadian Group of Seven and by Painters Eleven member Hortense Gordon, where she also subsequently taught design and applied arts 1916-1951, becoming head of the Institute in 1934), Gene entered an important phase of development, and with near reckless abandon, rented a considerable space, one that would endure the creation of large-scale works.

Additional studies during this time included day and evening classes for Life Drawing.

Though in the years to follow Gene engaged in numerous meetings and liaisons with artists, gallery owners/directors (Gallery Moos, Gallery 435, Carmen Lamanna Gallery, Canvas Gallery, Moore Gallery), and fine art collectors such as Irving Zucker, his pieces were rarely shown publicly.

His mission, however, continues to be the same: define and produce original works of art at the highest level.